发明授权
US4507313A Oxadiazolyl-imidazo-[1,4]benzodiazepines and their use in treatment of
diseases of the central nervous system
失效
恶二唑基 - 咪唑并[1,4]苯并二氮杂类及其在治疗中枢神经系统疾病中的应用
- 专利标题： Oxadiazolyl-imidazo-[1,4]benzodiazepines and their use in treatment of diseases of the central nervous system
- 专利标题（中）： 恶二唑基 - 咪唑并[1,4]苯并二氮杂类及其在治疗中枢神经系统疾病中的应用
-
申请号： US551818申请日： 1983-11-15
-
公开(公告)号： US4507313A公开(公告)日： 1985-03-26
- 发明人: Claus T. Braestrup , Joergen A. Christensen , Mogens Engelstoft , Frank Waetjen
- 申请人： Claus T. Braestrup , Joergen A. Christensen , Mogens Engelstoft , Frank Waetjen
- 申请人地址： DKX Soborg
- 专利权人： A/S Ferrosan
- 当前专利权人： A/S Ferrosan
- 当前专利权人地址： DKX Soborg
- 优先权： DKX5102/82 19821115
- 主分类号： A61K31/55
- IPC分类号： A61K31/55 ; A61P25/00 ; C07D487/04 ; A61K31/555 ; C07D521/00
摘要：
New oxadiazolyl-imidazo-[1,4]benzodiazepine derivatives having benzodiazepine receptor activity have the formula ##STR1## R' is hydrogen, chlorine, fluorine or nitro in the 7- or 8-position, R.sup.1 is hydrogen or lower alkyl of up to 3 carbon atoms,R.sup.3 is the oxadiazolyl grouping of the formula ##STR2## wherein R" is lower alkyl with up to 3 carbon atoms and A B is a grouping of the formula ##STR3## wherein R.sup.5 is hydrogen or methyl and R'" is hydrogen or chlorine. The compounds possess valuable pharmacological properties. In particular, they act on the central nervous system and are suitable for use in psychopharmaceutical preparations.
公开/授权文献
信息查询
