发明授权
US4521601A Practical total synthesis unnatural enantiomers of opium-derived
morphinans
失效
鸦片衍生的吗啡烷的实际全合成非天然对映异构体
- 专利标题: Practical total synthesis unnatural enantiomers of opium-derived morphinans
- 专利标题(中): 鸦片衍生的吗啡烷的实际全合成非天然对映异构体
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申请号: US477970申请日: 1983-03-23
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公开(公告)号: US4521601A公开(公告)日: 1985-06-04
- 发明人: Kenner C. Rice
- 申请人: Kenner C. Rice
- 申请人地址: DC Washington
- 专利权人: The United States of America as represented by the Department of Health & Human Services
- 当前专利权人: The United States of America as represented by the Department of Health & Human Services
- 当前专利权人地址: DC Washington
- 主分类号: C07D217/20
- IPC分类号: C07D217/20 ; C07D489/02 ; C07D221/28
摘要:
This invention relates to compounds which may be described as the unnatural enantiomers of morphine agonists and antagonists, which are useful as antitussives. The synthesis utilized is capable of producing all of the unnatural enantiomers of medically important opium derivatives of the morphinan type, including thebaine.
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