发明授权
US4560765A 3,7-Disubstituted-3-cephem-4-carboxylic acid compounds and processes for
preparation thereof
失效
3,7-二取代-3-头孢烯-4-羧酸化合物及其制备方法
- 专利标题： 3,7-Disubstituted-3-cephem-4-carboxylic acid compounds and processes for preparation thereof
- 专利标题（中）： 3,7-二取代-3-头孢烯-4-羧酸化合物及其制备方法
-
申请号： US571700申请日： 1984-01-18
-
公开(公告)号： US4560765A公开(公告)日： 1985-12-24
- 发明人: Takashi Kamiya , Kunihiko Tanaka , Yoshiharu Nakai , Kazuo Sakane
- 申请人： Takashi Kamiya , Kunihiko Tanaka , Yoshiharu Nakai , Kazuo Sakane
- 申请人地址： JPX Osaka
- 专利权人： Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人： Fujisawa Pharmaceutical Co., Ltd.
- 当前专利权人地址： JPX Osaka
- 优先权： GBX9425/76 19760309; GBX41145/76 19761004
- 主分类号： A61K31/545
- IPC分类号： A61K31/545 ; A61K31/546 ; A61P31/04 ; C07D277/20 ; C07D277/32 ; C07D277/34 ; C07D277/38 ; C07D277/40 ; C07D277/44 ; C07D277/46 ; C07D277/48 ; C07D277/52 ; C07D501/20 ; C07D501/22 ; C07D501/34 ; C07D501/36
摘要：
Antibiotic cephalosporin compounds, method of making and pharmaceutical composition thereof represented by the general formula ##STR1## wherein R.sup.1 is amino, lower alkylamino, a protected amino, a protected lower alkylamino, hydroxy or lower alkoxy,R.sup.2 is hydrogen, acyloxy, pyridium or a heterocyclicthio group which may have suitable substituent(s),R.sup.3 is carboxy or its derivative,A is carbonyl, hydroxy(lower)alkylene or a protected hydroxy(lower)alkylene andR.sup.4 is hydrogen or halogen, orR.sup.2 and R.sup.3 are linked together to represent a group of the formula --COO--, this divisional application being directed to intermediate compounds of the formula: ##STR2##
公开/授权文献
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