发明授权
- 专利标题： Novel Fredericamycin A derivatives
- 专利标题（中）： 新型弗雷德霉素A衍生物
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申请号： US639113申请日： 1984-08-09
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公开(公告)号： US4584377A公开(公告)日： 1986-04-22
- 发明人: Koichi Yokoi , Hiroshi Hasegawa , Tadashi Narita , Takemitsu Asaoka , Kenichi Kukita , Seiji Ishizeki , Toshiaki Nakashima
- 申请人： Koichi Yokoi , Hiroshi Hasegawa , Tadashi Narita , Takemitsu Asaoka , Kenichi Kukita , Seiji Ishizeki , Toshiaki Nakashima
- 申请人地址： JPX Tokyo
- 专利权人： SS Pharmaceutical Co., Ltd.
- 当前专利权人： SS Pharmaceutical Co., Ltd.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX58-150522 19830818; JPX58-165489 19830908; JPX58-166082 19830909
- 主分类号： C07D221/20
- IPC分类号： C07D221/20 ; C07D221/18
摘要：
Disclosed herein are Fredericamycin A derivatives, each, represented by the following general formula (I): ##STR1## wherein R means a hydrogen atom or acyl group, A denotes ##STR2## and dotted bonds are optional, with a proviso that when A is ##STR3## or the dotted bonds are contained, R is other than hydrogen atom. They have excellent antibacterial and antitumor activities and at the same time, are extremely stable compared with Fredericamycin A.
公开/授权文献
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