发明授权
US4593102A N-[(amino)alkyl]-1-pyrrolidine, 1-piperidine and
1-homopiperidinecarboxamides (and thiocarboxamides) with sulfur linked
substitution in the 2, 3 or 4-position
失效
在2,3或4位具有硫连接取代基的N - [（氨基）烷基] -1-吡咯烷，1-哌啶和1-高哌啶甲酰胺（和硫代羧酰胺）
- 专利标题： N-[(amino)alkyl]-1-pyrrolidine, 1-piperidine and 1-homopiperidinecarboxamides (and thiocarboxamides) with sulfur linked substitution in the 2, 3 or 4-position
- 专利标题（中）： 在2,3或4位具有硫连接取代基的N - [（氨基）烷基] -1-吡咯烷，1-哌啶和1-高哌啶甲酰胺（和硫代羧酰胺）
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申请号： US750156申请日： 1985-07-01
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公开(公告)号： US4593102A公开(公告)日： 1986-06-03
- 发明人: James R. Shanklin, Jr.
- 申请人： James R. Shanklin, Jr.
- 申请人地址： VA Richmond
- 专利权人： A. H. Robins Company, Inc.
- 当前专利权人： A. H. Robins Company, Inc.
- 当前专利权人地址： VA Richmond
- 主分类号： C07D207/34
- IPC分类号： C07D207/34 ; C07D207/36 ; C07D211/54 ; C07D223/06 ; C07D211/46
摘要：
Novel pyrrolidine, piperidine and homopiperidinecarboxamide and thiocarboxamide compounds having the formula: ##STR1## wherein X is --S--, --S(O)-- or --S(O).sub.2 --; A is a loweralkalene chain and A.sup.1 and A.sup.2 are alkalene chains when p and d are one; R, R.sup.1 and R.sup.2 are hydrogen, loweralkyl, phenyl cycloalkyl or phenylalkyl and R.sup.1 and R.sup.2 may form a heterocyclic residue with the adjacent nitrogen atom; Q is a selected aromatic radical, and the pharmaceutically acceptable acid addition salts useful as cardiac antiarrhythmia agents are disclosed.Novel chemical intermediates, unsubstituted on pyrrolidine, piperidine and homopiperidine nitrogen but with --(A.sup.2).sub.p --X--(A.sup.2).sub.d --Q side chain are also disclosed.
公开/授权文献
- US5733147A Sim card connector 公开/授权日：1998-03-31
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