发明授权
- 专利标题： Selective halogenation of 6-hydroxy picoline derivatives
- 专利标题（中）： 6-羟基甲基吡啶衍生物的选择性卤化
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申请号： US710262申请日： 1985-03-11
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公开(公告)号： US4594422A公开(公告)日： 1986-06-10
- 发明人: Jon A. Orvik
- 申请人： Jon A. Orvik
- 申请人地址： MI Midland
- 专利权人： The Dow Chemical Company
- 当前专利权人： The Dow Chemical Company
- 当前专利权人地址： MI Midland
- 主分类号： C07D213/79
- IPC分类号： C07D213/79 ; C07D211/84
摘要：
The invention relates to a method for selective halogenation of 6-hydroxy picoline derivatives such as 6-hydroxy picolinic acid and 6-hydroxy picoline. When 6-hydroxy picolinic acid is halogenated by allowing it to stand in an aqueous mineral acid solution for a sufficient period to replace the halo substituent with a hydroxy substituent, and then halogenated, an improved yield of the 3-halo, 6-hydroxy picolinic acid to the 5-halo 6-hydroxy picolinic acid is obtained.
公开/授权文献
- US5148615A Dredging apparatus 公开/授权日：1992-09-22
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