发明授权
US4611081A Process for the preparation of HMG-CoA reductase inhibitors intermediates
失效
HMG-CoA还原酶抑制剂中间体的制备方法
- 专利标题: Process for the preparation of HMG-CoA reductase inhibitors intermediates
- 专利标题(中): HMG-CoA还原酶抑制剂中间体的制备方法
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申请号: US752323申请日: 1985-07-05
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公开(公告)号: US4611081A公开(公告)日: 1986-09-09
- 发明人: Joseph E. Lynch , Ichiro Shinkai , Ralph P. Volante
- 申请人: Joseph E. Lynch , Ichiro Shinkai , Ralph P. Volante
- 申请人地址: NJ Rahway
- 专利权人: Merck & Co., Inc.
- 当前专利权人: Merck & Co., Inc.
- 当前专利权人地址: NJ Rahway
- 主分类号: C07C69/716
- IPC分类号: C07C69/716 ; C07C67/44 ; C07C69/675 ; C07C69/732 ; C07C69/738 ; C07C69/76 ; C07C69/74
摘要:
A novel process for intermediates in the synthesis and hypercholesterolemic compounds of the HMG-CoA reductase type of the following general formula (1): ##STR1## involving an enantioselective aldol condensation is disclosed.
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