发明授权
- 专利标题: Aroyl substituted dihydro-1,4-thiazines
- 专利标题(中): 芳酰基取代的二氢-1,4-噻嗪
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申请号: US625946申请日: 1984-06-29
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公开(公告)号: US4622322A公开(公告)日: 1986-11-11
- 发明人: Harris B. Renfroe
- 申请人: Harris B. Renfroe
- 申请人地址: NY Ardsley
- 专利权人: Ciba-Geigy Corporation
- 当前专利权人: Ciba-Geigy Corporation
- 当前专利权人地址: NY Ardsley
- 主分类号: A61K31/54
- IPC分类号: A61K31/54 ; A61P29/00 ; C07C45/63 ; C07C49/80 ; C07C67/00 ; C07C313/00 ; C07C315/04 ; C07C317/28 ; C07C317/48 ; C07C323/25 ; C07C323/29 ; C07D209/48 ; C07D213/50 ; C07D279/12 ; C07D417/06 ; C07D279/10
摘要:
Compounds of the formula ##STR1## wherein Ar is pyridyl or phenyl substituted by halogen, halo-C.sub.1 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkoxy, or carboxy-C.sub.1 -C.sub.4 -alkyl, n is zero, one or two, R.sub.1 is hydrogen, C.sub.1 -C.sub.4 -alkyl, heterocyclyl-C.sub.2 -C.sub.4 -alkyl, amino-C.sub.2 -C.sub.4 -alkyl, C.sub.1 -C.sub.4 -alkylamino-C.sub.2 -C.sub.4 -alkyl, di-C.sub.1 -C.sub.4 -alkylamino-C.sub.2 -C.sub.4 -alkylor C.sub.1 -C.sub.4 -alkanoyl, and R.sub.2 is hydrogen, carboxy-C.sub.1 -C.sub.4 -alkyl, or C.sub.1 -C.sub.4 -alkoxy-carbonyl-C.sub.1 -C.sub.4 -alkyl are disclosed as well as their preparation, pharmaceutical compositions containing the same and the use thereof as antirheumatic agents.
公开/授权文献
- US5220317A Electrochromic device capable of prolonged coloration 公开/授权日:1993-06-15
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