发明授权
- 专利标题： Process for the preparation and purification of peptides
- 专利标题（中）： 肽的制备和纯化方法
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申请号： US667025申请日： 1984-11-01
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公开(公告)号： US4623716A公开(公告)日： 1986-11-18
- 发明人: David Stevenson , Mohammad A. Islam
- 申请人： David Stevenson , Mohammad A. Islam
- 申请人地址： PA Ft. Washington
- 专利权人： USV Pharmaceutical Corp.
- 当前专利权人： USV Pharmaceutical Corp.
- 当前专利权人地址： PA Ft. Washington
- 主分类号： C07K1/00
- IPC分类号： C07K1/00 ; A61K38/00 ; C07K1/02 ; C07K1/06 ; C07K1/113 ; C07K7/16 ; C07K14/575 ; C07K14/585 ; C07K14/655
摘要：
Peptides, such as calcitonin, having two cysteine residues connected by a disulfide bond are prepared by a process which includes the step of cyclizing the cysteines at a pH of 8.5 to 9.0, and a concentration of 0.4 to 1.8 mg of peptide per ml of solution. These novel conditions produce rapid cyclization with an unforeseen improvement in yield.
公开/授权文献
- US5919667A Modular assembly retroviral vectors and uses thereof 公开/授权日：1999-07-06
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