发明授权
- 专利标题： Method for the immunoanalysis of cholesterol epoxides
- 专利标题（中）： 胆固醇环氧化物免疫分析方法
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申请号： US673768申请日： 1984-11-21
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公开(公告)号： US4639420A公开(公告)日： 1987-01-27
- 发明人: Carl P. Schaffner
- 申请人： Carl P. Schaffner
- 专利权人： Schaffner Carl P
- 当前专利权人： Schaffner Carl P
- 主分类号： G01N33/53
- IPC分类号： G01N33/53 ; C07J9/00 ; C07J31/00 ; C07J41/00 ; C07J43/00 ; C07J71/00 ; C12Q1/48 ; C12Q1/60 ; G01N33/531 ; G01N33/533 ; G01N33/534 ; G01N33/566 ; G01N33/92
摘要：
An immunoassay is provided for cholesterol epoxide. To prepare the antibodies used in the immunoassay, novel immunogens, are prepared which comprise a 3,5(6)-transdiaxial-dihydroxycholestane-6(5)-yl-hapten adduct linked to a covalently bonded bridge to a carrier protein. To detect cholesterol epoxide in the sample, it is converted to the hapten adduct, then contacted with the selected antibody.
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