发明授权
- 专利标题: Derivatives of glycinamide, their preparation and their use
- 专利标题(中): 甘氨酰胺的衍生物,其制备及其用途
-
申请号: US768185申请日: 1985-08-23
-
公开(公告)号: US4639468A公开(公告)日: 1987-01-27
- 发明人: Romeo Roncucci , Claude L. Gillet , Alexis H. Cordi , Mark A. Martens , Joseph L. Roba , Paul J. Niebes , Georges E. Lambelin , William R. Van Dorsser
- 申请人: Romeo Roncucci , Claude L. Gillet , Alexis H. Cordi , Mark A. Martens , Joseph L. Roba , Paul J. Niebes , Georges E. Lambelin , William R. Van Dorsser
- 申请人地址: BEX Brussels
- 专利权人: Continental Pharma Inc.
- 当前专利权人: Continental Pharma Inc.
- 当前专利权人地址: BEX Brussels
- 优先权: LUX81068 19790322; LUX81069 19790322
- 主分类号: A61K31/16
- IPC分类号: A61K31/16 ; A61K31/165 ; A61K31/195 ; A61K31/205 ; C07C233/00 ; C07C233/12 ; C07C233/30 ; C07C237/00 ; C07C271/06 ; C07C271/22
摘要:
A glycinamide derivative of the general formula I: ##STR1## wherein: R is a linear or ramified alkyl group C.sub.5 -C.sub.18, a linear or ramified alkenyl group C.sub.5, C.sub.6, C.sub.7, C.sub.8, C.sub.9, C.sub.10, C.sub.11, C.sub.12, C.sub.13, C.sub.14, C.sub.15, C.sub.16, C.sub.17 or C.sub.18, a linear or ramified alkynyl group C.sub.4 -C.sub.10, a linear or ramified acyl group C.sub.4 -C.sub.18, a linear or ramified alkyl group C.sub.1 -C.sub.10, substituted by a phenoxy group, by a hydroxy radical, by an acetoxy radical, by a carboxy radical, by a linear or ramified alkoxycarbonyl group C.sub.1 -C.sub.4, by a carbonyl radical, by a carboxaldehyde group, by an acetal or cetal group, by one or more phenyl groups, by one or more phenyl groups substituted by a halogen atom such as fluorine, chlorine or bromine,R.sub.1 represents hydrogen, a linear or ramified alkyl group C.sub.1, C.sub.2, C.sub.3, C.sub.4, C.sub.5, C.sub.6, C.sub.7, C.sub.8, C.sub.9 or C.sub.10, a linear or ramified acyl group C.sub.1 -C.sub.6, a benzoyl group, a linear or ramified alkoxycarbonyl group C.sub.1, C.sub.2, C.sub.3, C.sub.4, C.sub.5, C.sub.6, C.sub.7 or C.sub.8, a carboxamidomethyl group,R.sub.2 represents hydrogen, a linear or ramified alkyl C.sub.1, C.sub.2, C.sub.3, a phenyl group,R.sub.3 represents hydrogen, a linear or ramified alkyl group C.sub.1, C.sub.2, C.sub.3, C.sub.4, C.sub.5, C.sub.6, C.sub.7 or C.sub.8, a phenyl group, optionally substituted by a halogen atom, such as fluorine, chlorine or bromine,R.sub.4 represents hydrogen, a linear or ramified alkyl group C.sub.1, C.sub.2, C.sub.3, C.sub.4, C.sub.5, C.sub.6, C.sub.7 or C.sub.8 as well as salts of these derivatives with non toxic and pharmaceutically usable acids.
公开/授权文献
- US5195528A Acoustic respiration detector 公开/授权日:1993-03-23
信息查询