发明授权
US4656083A Plasma gas discharge treatment for improving the biocompatibility of
biomaterials
失效
用于提高生物材料生物相容性的等离子体气体放电处理
- 专利标题： Plasma gas discharge treatment for improving the biocompatibility of biomaterials
- 专利标题（中）： 用于提高生物材料生物相容性的等离子体气体放电处理
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申请号： US709990申请日： 1985-03-11
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公开(公告)号： US4656083A公开(公告)日： 1987-04-07
- 发明人: Allan S. Hoffman , Andrew Garfinkle , Buddy D. Ratner , Stephen R. Hanson
- 申请人： Allan S. Hoffman , Andrew Garfinkle , Buddy D. Ratner , Stephen R. Hanson
- 申请人地址： WA Seattle
- 专利权人： Washington Research Foundation
- 当前专利权人： Washington Research Foundation
- 当前专利权人地址： WA Seattle
- 主分类号： A61F2/06
- IPC分类号： A61F2/06 ; A61L27/50 ; A61L33/00 ; B05D3/14 ; B05D7/24 ; B05D3/06
摘要：
A method of treating articles to improve their biocompatibility is disclosed. A substrate material is positioned within a reactor vessel and exposed to plasma gas discharge in the presence of an atmosphere of an inert gas and then in the presence of an organic gas, such as a halocarbon or halohydrocarbon gas, capable of forming a thin, biocompatible surface covalently bonded to the surface of the substrate. The method is particularly useful in the treatment of vascular graft materials to improve their biocompatibility.
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