发明授权
US4677111A N-benzoyl-N'-(3-nitrophenyl) urea compounds, and antitumorous
compositions containing them
失效
N-苯甲酰基-N' - （3-硝基苯基）脲化合物和含有它们的抗肿瘤组合物
- 专利标题： N-benzoyl-N'-(3-nitrophenyl) urea compounds, and antitumorous compositions containing them
- 专利标题（中）： N-苯甲酰基-N' - （3-硝基苯基）脲化合物和含有它们的抗肿瘤组合物
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申请号： US782570申请日： 1985-10-01
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公开(公告)号： US4677111A公开(公告)日： 1987-06-30
- 发明人: Takahiro Haga , Nobutoshi Yamada , Hideo Sugi , Toru Koyanagi , Hiroshi Okada
- 申请人： Takahiro Haga , Nobutoshi Yamada , Hideo Sugi , Toru Koyanagi , Hiroshi Okada
- 申请人地址： JPX Osaka
- 专利权人： Ishihara Sangyo Kaisha Ltd.
- 当前专利权人： Ishihara Sangyo Kaisha Ltd.
- 当前专利权人地址： JPX Osaka
- 优先权： JPX59-213718 19841012
- 主分类号： C07D213/64
- IPC分类号： C07D213/64 ; A61K31/44 ; A61K31/4418 ; A61K31/50 ; A61K31/505 ; A61P35/00 ; C07D213/643 ; C07D237/14 ; C07D239/34 ; C07D237/12 ; C07D239/30
摘要：
An N-benzoyl-N'-(3-nitrophenyl) urea compound having the formula ##STR1## wherein each of X.sub.1 and X.sub.2 is a hydrogen atom, a halogen atom, a trifluoromethyl group or a nitro group, and Y is ##STR2## (wherein R is a hydrogen atom, a halogen atom or a tirfluoromethyl group), provided that when Y is ##STR3## X.sub.1 and/or X.sub.2 is a nitro group. The compound is useful as an active ingredient of an antitumorous composition.
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