发明授权
US4690935A Inhibition of tumor growth and metastasis with calcium channel blocker
compounds
失效
用钙通道阻滞剂化合物抑制肿瘤生长和转移
- 专利标题： Inhibition of tumor growth and metastasis with calcium channel blocker compounds
- 专利标题（中）： 用钙通道阻滞剂化合物抑制肿瘤生长和转移
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申请号： US480704申请日： 1983-03-31
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公开(公告)号： US4690935A公开(公告)日： 1987-09-01
- 发明人: John D. Taylor , Kenneth V. Honn
- 申请人： John D. Taylor , Kenneth V. Honn
- 申请人地址： MI Detroit
- 专利权人： Wayne State University
- 当前专利权人： Wayne State University
- 当前专利权人地址： MI Detroit
- 主分类号： A61K31/135
- IPC分类号： A61K31/135 ; A61K31/275 ; A61K31/44 ; A61K31/455 ; A61K31/495 ; A61K31/55 ; A61P35/00 ; C07D211/90 ; A61K31/125
摘要：
The use of calcium channel blocker compounds as antitumor and antimetastatic agents in mammals in vivo and in standard laboratory experimets with tumor cells in vitro is described. In particular the use of nimodipine (Bay e 9736) or nifedipine (Bay a 1040) and structurally related compounds as described.
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