发明授权
- 专利标题: Novel intermediates for the preparation of 7-hydroxy-indoles
- 专利标题(中): 用于制备7-羟基 - 吲哚的新型中间体
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申请号: US29086申请日: 1987-03-23
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公开(公告)号: US4736034A公开(公告)日: 1988-04-05
- 发明人: Lucien Nedelec , Patrick Fauveau , Gilles Hamon , Claude Oberlander
- 申请人: Lucien Nedelec , Patrick Fauveau , Gilles Hamon , Claude Oberlander
- 申请人地址: FRX Paris
- 专利权人: Roussel Uclaf
- 当前专利权人: Roussel Uclaf
- 当前专利权人地址: FRX Paris
- 优先权: FRX8503585 19850312
- 主分类号: C07D211/22
- IPC分类号: C07D211/22 ; A61K31/4427 ; A61K31/445 ; A61K31/451 ; A61P9/00 ; A61P9/04 ; A61P9/08 ; A61P9/12 ; A61P25/00 ; A61P25/02 ; C07D211/26 ; C07D211/42 ; C07D211/70 ; C07D401/04
摘要:
A compound selected from the group consisting of a compound of the formulae ##STR1## wherein R.sub.1 ' is selected from the group consisting of alkoxy of 1 to 5 carbon atoms, phenoxy and phenylalkoxy of 7 to 9 carbon atoms, R' is selected from the group consisting of alkyl of 1 to 5 carbon atoms, cycloalkylalkyl of 4 to 7 carbon atoms and phenyl alkyl of 7 to 12 carbon atoms optionally substituted with one or more members of the group consisting of alkyl of 1 to 5 carbon atoms, alkoxy of 1 to 5 carbon atoms, halogen and alkenyl of 3 to 5 carbon atoms and alkynyl of 3 to 5 carbon atoms with the proviso that the multiple bond is not between the carbons .alpha.- and .beta. to the nitrogen atom and B is a reversible secondary amine blocking group and their haloamines.
公开/授权文献
- US5952542A Method of oxidation 公开/授权日:1999-09-14
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