发明授权
- 专利标题： Method and cell line for obtaining plasminogen activators
- 专利标题（中）： 用于获得纤溶酶原激活物的方法和细胞系
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申请号： US704593申请日： 1985-02-22
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公开(公告)号： US4757005A公开(公告)日： 1988-07-12
- 发明人: Sham Y. Chan
- 申请人： Sham Y. Chan
- 申请人地址： IN Elkhart
- 专利权人： Miles Inc.
- 当前专利权人： Miles Inc.
- 当前专利权人地址： IN Elkhart
- 主分类号： C12N9/64
- IPC分类号： C12N9/64 ; C12N9/72 ; C12R1/91 ; C12P21/00 ; C12N5/00
摘要：
A method of increasing the yield of plasminogen activator from a plasminogen activator-producing cell line by adapting said cell line to grow in a suitable growth medium essentially free of fetal calf serum is disclosed. Also disclosed are cell lines capable of producing relatively large quantities of plasminogen activator, and a chemically defined growth medium suitable for adapting a plasminogen activator-secreting cell line to growth in the absence of fetal calf serum.
公开/授权文献
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