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US4769451A Synthesis of carbapenems using n-substituted azetidinones 失效
用n-取代的氮杂环丁酮合成碳青霉烯

Synthesis of carbapenems using n-substituted azetidinones
摘要:
A novel process is disclosed for converting known 3,4-disubstituted azetidinones to carbapenems. The process proceeds through novel N-substituted intermediates and then cyclizes to the 4-position of the azetidinone to form the carbapenem.
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