发明授权
US4777257A Certain tetrahydronaphthyl or indanylcarboxylates and derivatives
thereof which inhibit the synthesis of thromboxane
失效
抑制合成凝血恶烷的某些四氢萘基或二氢化茚羧酸盐及其衍生物
- 专利标题： Certain tetrahydronaphthyl or indanylcarboxylates and derivatives thereof which inhibit the synthesis of thromboxane
- 专利标题（中）： 抑制合成凝血恶烷的某些四氢萘基或二氢化茚羧酸盐及其衍生物
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申请号： US901694申请日： 1986-08-29
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公开(公告)号： US4777257A公开(公告)日： 1988-10-11
- 发明人: Munefumi Kanao
- 申请人： Munefumi Kanao
- 申请人地址： JPX Tokyo
- 专利权人： Daiichi Seiyaku Co., Ltd.
- 当前专利权人： Daiichi Seiyaku Co., Ltd.
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX58-155561 19830825; JPX59-102278 19840521; JPX59-112438 19840601; JPX59-120557 19840612; JPX59-139525 19840705; JPX59-147252 19840716
- 主分类号： C07C33/34
- IPC分类号： C07C33/34 ; C07C33/50 ; C07C57/62 ; C07C62/36 ; C07D213/55 ; C07D233/56 ; C07D233/58 ; C07D233/60 ; C07D233/84 ; C07D277/30 ; C07D277/40 ; C07D521/00 ; C07D277/32
摘要：
Benzocycloalkane derivatives of the formula (I) ##STR1## wherein: Z represents a methylene group or an ethylene group, either one of R.sup.1 and R.sup.2 represents --(CH.sub.2).sub.m --COOR.sup.3 and the other represents ##STR2## wherein R.sup.3 represents a hydrogen atom or an alkyl group having 1 to 6 carbon atoms, n represents an interger of 1 to 6 and m represents an interger of 0 to 5, and the physiologically acceptable salts thereof; having a strong and selective inhibition activity of thromboxane A.sub.2 synthesis.
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