发明授权
US4791128A Rhizoxin esters and salts, their pharmaceutical use as anti-tumor agents
失效
根瘤菌素酯和盐,它们的药物用作抗肿瘤剂
- 专利标题: Rhizoxin esters and salts, their pharmaceutical use as anti-tumor agents
- 专利标题(中): 根瘤菌素酯和盐,它们的药物用作抗肿瘤剂
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申请号: US143314申请日: 1988-01-11
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公开(公告)号: US4791128A公开(公告)日: 1988-12-13
- 发明人: Shigenobu Okuda , Shigeo Iwasaki , Michio Namikoshi , Masao Arakawa , Fusaaki Shimizu
- 申请人: Shigenobu Okuda , Shigeo Iwasaki , Michio Namikoshi , Masao Arakawa , Fusaaki Shimizu
- 申请人地址: JPX Tokyo
- 专利权人: Sankyo Company Limited
- 当前专利权人: Sankyo Company Limited
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX60-39399 19850228
- 主分类号: A61K31/365
- IPC分类号: A61K31/365 ; A61P35/00 ; C07D493/04 ; C07D493/14 ; C07D493/18 ; C07D493/22 ; A61K31/42
摘要:
Acylated derivatives of rhizoxin and of rhizoxin-2-ene may be prepared by reacting rhizoxin or rhizoxin-2-ene with an acid or reactive derivative thereof. They have excellent anti-tumor activity.
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