Invention Grant
US4804787A Processes and intermediates for making 16-phenoxy and 16-substituted
phenoxy-prostatrienoic acid derivatives
失效
制备16-苯氧基和16-取代的苯氧基 - 前列腺烯酸衍生物的方法和中间体
- Patent Title: Processes and intermediates for making 16-phenoxy and 16-substituted phenoxy-prostatrienoic acid derivatives
- Patent Title (中): 制备16-苯氧基和16-取代的苯氧基 - 前列腺烯酸衍生物的方法和中间体
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Application No.: US785934Application Date: 1985-10-09
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Publication No.: US4804787APublication Date: 1989-02-14
- Inventor: Gary F. Cooper , Douglas L. Wren , Albert R. Van Horn , Tsung-Tee Li , Colin C. Beard
- Applicant: Gary F. Cooper , Douglas L. Wren , Albert R. Van Horn , Tsung-Tee Li , Colin C. Beard
- Applicant Address: CA Palo Alto
- Assignee: Syntex (U.S.A.) Inc.
- Current Assignee: Syntex (U.S.A.) Inc.
- Current Assignee Address: CA Palo Alto
- Main IPC: C07C405/00
- IPC: C07C405/00 ; C07F7/18 ; C07C41/00
Abstract:
This invention relates to a process for making an enantiomer or racemic mixture of a compound of the formula ##STR1## wherein R is hydrogen, lower alkyl or a pharmaceutically acceptable, non-toxic salt of a compound wherein R is hydrogen; X is hydrogen, halo, trifluoromethyl, lower alkyl or lower alkoxy, and the wavy lines represent the .alpha. or .beta. configuration with the proviso that when one wavy line is .alpha. the other is .beta.; novel intermediates useful for preparing these compounds; and processes for making the intermediates.
Public/Granted literature
- US5815902A Rotary transfer machine Public/Granted day:1998-10-06
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