发明授权
- 专利标题： Derivatives of quinuclidine
- 专利标题（中）： 奎宁环的衍生物
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申请号： US853404申请日： 1986-04-18
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公开(公告)号： US4855290A公开(公告)日： 1989-08-08
- 发明人: Abraham Fisher , Ishai Karton , Eliahu Heldman , Aharon Levy , Yona Grunfeld
- 申请人： Abraham Fisher , Ishai Karton , Eliahu Heldman , Aharon Levy , Yona Grunfeld
- 申请人地址： ILX Ness-Ziona
- 专利权人： State of Israel, represented by Prime Minister's Office, Israel Institute for Biological Research
- 当前专利权人： State of Israel, represented by Prime Minister's Office, Israel Institute for Biological Research
- 当前专利权人地址： ILX Ness-Ziona
- 优先权： ILX75166 19850510; ILX77568 19860110
- 主分类号： A61K31/435
- IPC分类号： A61K31/435 ; A61K38/04 ; A61P25/00 ; A61P25/02 ; A61P25/04 ; A61P25/26 ; A61P25/28 ; C07D327/00 ; C07D453/02 ; C07D497/20
摘要：
Quinuclidine derivatives having the general formula (I) ##STR1## and geometrical isomers, enantiomers, diastereoisomers, racemates and/or acid addition salts thereof, wherein Z represents the group >CR.sup.1 R.sup.2 or two hydrogen atoms; and R.sup.1 and R.sup.2, which may be identical or different, are each alkyl, cyclopentyl, cyclohexyl, aryl, or diarylmethylol, or alkyl which is substituted by one or more aryl groups, or one of R.sup.1 and R.sup.2 may be hydrogen.
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