发明授权
US4857520A Fused azepinone and azocinone derivatives, processes for their
preparation, agents containing them and their use, and intermediates in
their preparation
失效
稠合氮杂酮和azocinone衍生物,其制备方法,含有它们的试剂及其用途及其制备中间体
- 专利标题: Fused azepinone and azocinone derivatives, processes for their preparation, agents containing them and their use, and intermediates in their preparation
- 专利标题(中): 稠合氮杂酮和azocinone衍生物,其制备方法,含有它们的试剂及其用途及其制备中间体
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申请号: US155595申请日: 1988-02-12
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公开(公告)号: US4857520A公开(公告)日: 1989-08-15
- 发明人: Hansjorg Urbach , Rainer Henning , Bernward Scholkens , Reinhard Becker
- 申请人: Hansjorg Urbach , Rainer Henning , Bernward Scholkens , Reinhard Becker
- 申请人地址: DEX Frankfurt
- 专利权人: Hoechst Aktiengesellschaft
- 当前专利权人: Hoechst Aktiengesellschaft
- 当前专利权人地址: DEX Frankfurt
- 优先权: DEX3704661 19870214
- 主分类号: C07D223/32
- IPC分类号: C07D223/32 ; A61K31/395 ; A61K31/445 ; A61K31/55 ; A61K38/00 ; A61P9/00 ; A61P9/12 ; A61P27/02 ; A61P27/06 ; A61P43/00 ; C07D225/04 ; C07D401/12 ; C07D403/06 ; C07D403/12 ; C07D405/12 ; C07K5/02
摘要:
The invention relates to compounds of the formula I ##STR1## in which m denotes 1 or 2 and n denotes, 0, 1 or 2; R.sup.1 and R.sup.2 denote identical or different radicals from the series comprising hydrogen, optionally substituted alkyl, alkenyl, cycloalkyl, cycloalkenyl, cycloalkylalkyl, partly hydrogenated aryl and optionally substituted aralkyl; R.sup.3 and R.sup.4 denote identical or different radicals from the series comprising hydrogen, alkyl, alkenyl and optionally substituted aralkyl; Y denotes hydrogen or hydroxyl and Z denotes hydrogen, or Y and Z together denote oxo, and X denotes optionally substituted alkyl, alkenyl, cycloalkyl, optionally substituted 4-piperidinyl, optionally substituted aryl or indolyl, processes for their preparation, medicaments containing these compounds and their use, and to intermediates in their preparation.
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