发明授权
- 专利标题： Antihistaminic benzimidazole derivatives
- 专利标题（中）： 抗组胺苯并咪唑衍生物
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申请号： US222758申请日： 1988-07-22
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公开(公告)号： US4857536A公开(公告)日： 1989-08-15
- 发明人: Philippe Manoury , Guy Rossey , Jean Binet , Gerard DeFosse , Najib Jabri
- 申请人： Philippe Manoury , Guy Rossey , Jean Binet , Gerard DeFosse , Najib Jabri
- 申请人地址： FRX Paris
- 专利权人： Synthelabo
- 当前专利权人： Synthelabo
- 当前专利权人地址： FRX Paris
- 优先权： FRX8710409 19870723
- 主分类号： A61K31/445
- IPC分类号： A61K31/445 ; A61K31/4427 ; A61P37/08 ; C07D401/04
摘要：
A compound which is a benzimidazole derivative of formula (I) ##STR1## in which: R.sub.1 is hydrogen or methyl,R.sub.2 is hydrogen, methyl or acetyl,R.sub.3 is hydrogen, methyl or acetyl, andR.sub.4 is hydrogen or a halogen,or a pharmaceutically acceptable acid addition salt thereof.The compounds have histamine antagonist activity and are also synthesis intermediates.
公开/授权文献
- US6062097A Automatic speed-change apparatus for a gear transmission 公开/授权日：2000-05-16
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