发明授权
- 专利标题: Antibody-therapeutic agent conjugates
- 专利标题(中): 抗体治疗剂缀合物
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申请号: US650375申请日: 1984-09-13
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公开(公告)号: US4867973A公开(公告)日: 1989-09-19
- 发明人: John W. F. Goers , Hurley D. King , Chyi Lee , Daniel J. Coughlin , Vernon L. Alvarez , John D. Rodwell , Thomas J. McKearn
- 申请人: John W. F. Goers , Hurley D. King , Chyi Lee , Daniel J. Coughlin , Vernon L. Alvarez , John D. Rodwell , Thomas J. McKearn
- 申请人地址: NJ Princeton
- 专利权人: Cytogen Corporation
- 当前专利权人: Cytogen Corporation
- 当前专利权人地址: NJ Princeton
- 主分类号: A61K41/00
- IPC分类号: A61K41/00 ; A61K47/48 ; A61K51/10 ; C07K5/083 ; G01N33/532 ; G01N33/534
摘要:
This invention relates to antibody-therapeutic agent conjugates having a therapeutic agent covalently attached to an antibody or antibody fragment. Also described are methods for intermediates in the preparation of antibody conjugates. Therapeutic in vivo methods utilizing such antibody-therapeutic agent conjugates are described.
公开/授权文献
- US5810128A Shock absorber 公开/授权日:1998-09-22
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