发明授权
- 专利标题: Pyrimidine derivatives
- 专利标题(中): 嘧啶衍生物
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申请号: US79741申请日: 1987-07-30
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公开(公告)号: US4882316A公开(公告)日: 1989-11-21
- 发明人: Robert W. Lambert , Joseph A. Martin , Gareth J. Thomas
- 申请人: Robert W. Lambert , Joseph A. Martin , Gareth J. Thomas
- 申请人地址: NJ Nutley
- 专利权人: Hoffmann-La Roche Inc.
- 当前专利权人: Hoffmann-La Roche Inc.
- 当前专利权人地址: NJ Nutley
- 优先权: GBX8619424 19860808; GBX8710777 19870507
- 主分类号: C07D405/06
- IPC分类号: C07D405/06 ; A61K31/505 ; A61K31/70 ; A61K31/7042 ; A61K31/7052 ; A61K31/7064 ; A61K31/7068 ; A61K31/7072 ; A61P31/12 ; C07D405/04 ; C07H19/06 ; C12N9/99
摘要:
Compounds of the formula ##STR1## wherein R.sup.1 is halogen, C.sub.1-4 -alkyl or halo-(C.sub.1-4 - alkyl), R.sup.2 is hydrogen, hydroxy or acyloxy, R.sup.3 and R.sup.4 each are hydrogen or C.sub.1-4 -alkyl, R.sup.5 is aryl or aryloxy, X is O or NH and Y is --CO--CH.sub.2 --, --CH(OH)--CH.sub.2 --, --CH.sub.2 --CH.sub.2 --, --S--, --SO-- or --SO.sub.2 --,and tautomers thereof are described. Compounds of formula I and their tautomers possess antiviral activity and can be used in the form of medicaments for the control and prevention of viral infections.
公开/授权文献
- US6099864A In situ activation of microcapsules 公开/授权日:2000-08-08