发明授权
US4889860A Oximes of oxymorphone, naltrexone and naloxone as potent, selective
opioid receptor agonists and antagonists
失效
羟吗啡酮，纳曲酮和纳洛酮作为有效的选择性阿片受体激动剂和拮抗剂
- 专利标题： Oximes of oxymorphone, naltrexone and naloxone as potent, selective opioid receptor agonists and antagonists
- 专利标题（中）： 羟吗啡酮，纳曲酮和纳洛酮作为有效的选择性阿片受体激动剂和拮抗剂
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申请号： US35034申请日： 1987-04-06
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公开(公告)号： US4889860A公开(公告)日： 1989-12-26
- 发明人: Waclaw J. Rzeszotarski , Babu J. Mavunkel
- 申请人： Waclaw J. Rzeszotarski , Babu J. Mavunkel
- 申请人地址： MD Baltimore
- 专利权人： Nova Pharmaceutical Corporation
- 当前专利权人： Nova Pharmaceutical Corporation
- 当前专利权人地址： MD Baltimore
- 主分类号： C07D489/08
- IPC分类号： C07D489/08
摘要：
A potent, selective opioid receptor agonist or antagonist exhibiting properties useful for a longacting analgesic or opiate abuse treatment agent or appetite suppressant having the general formula: ##STR1## wherein R is methyl, cyclopropylmethyl or allyl, and R.sub.1 is an unsubstituted or substituted aryl, aralkyl, heteroaryl, heteroaralkyl or a cycloalkyl group with or without a heteroatom like S,O,N; and the pharmaceutically acceptable salts thereof.
公开/授权文献
- US6021296A Magnet roller and manufacturing method thereof 公开/授权日：2000-02-01
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