发明授权
- 专利标题： 6-fluoroprostaglandins
- 专利标题（中）： 6-氟前列腺素
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申请号： US257808申请日： 1988-10-14
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公开(公告)号： US4906663A公开(公告)日： 1990-03-06
- 发明人: Naonobu Hatano , Buichi Fujitani , Toshiaki Kadokawa , Yasushi Matsumura , Tomoyuki Asai , Arata Yasuda , Keiichi Uchida
- 申请人： Naonobu Hatano , Buichi Fujitani , Toshiaki Kadokawa , Yasushi Matsumura , Tomoyuki Asai , Arata Yasuda , Keiichi Uchida
- 申请人地址： JPX Tokyo JPX Osaka
- 专利权人： Asahi Glass Company, Ltd.,Dainippon Pharmaceutical Company, Ltd.
- 当前专利权人： Asahi Glass Company, Ltd.,Dainippon Pharmaceutical Company, Ltd.
- 当前专利权人地址： JPX Tokyo JPX Osaka
- 优先权： JPX62-259649 19871016
- 主分类号： A61K31/557
- IPC分类号： A61K31/557 ; A61K31/5575 ; A61P1/04 ; A61P7/02 ; A61P9/08 ; A61P9/10 ; C07C67/00 ; C07C401/00 ; C07C405/00
摘要：
A 6-fluoroprostaglandin having the formula: ##STR1## wherein A is a carbonyl group or a hydroxymethylene group, R.sup.1 is a substituted or unsubstituted C.sub.1 -C.sub.10 alkyl group or a substituted or unsubstituted 5- or 6-membered cycloalkyl group, R.sup.2 is a hydrogen atom or a C.sub.1 -C.sub.10 alkyl group, each of R.sup.3 and R.sup.4 which may be the same or different is a hydrogen atom or a protecting group, R.sup.5 is a hydrogen atom or a hydroxyl group, and is a single bond or a double bond, and its salt when R.sup.2 is a hydrogen atom.
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