发明授权
- 专利标题: Quinoline thioethers
- 专利标题(中): 喹啉硫醚
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申请号: US184796申请日: 1988-04-22
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公开(公告)号: US4921960A公开(公告)日: 1990-05-01
- 发明人: Jozsef Knoll , Katalin Budai nee Simonyi , Edit Berenyi nee Poldermann , Ildiko Miklya , Marton Fekete , Gabriella Zsilla , Berta Knoll , Attila Mandi , Lujza Petocz , Istvan Gyertyan , Istvan Gacsalyi
- 申请人: Jozsef Knoll , Katalin Budai nee Simonyi , Edit Berenyi nee Poldermann , Ildiko Miklya , Marton Fekete , Gabriella Zsilla , Berta Knoll , Attila Mandi , Lujza Petocz , Istvan Gyertyan , Istvan Gacsalyi
- 申请人地址: DEX Ludwigshafen
- 专利权人: BASF Aktiengesellschaft
- 当前专利权人: BASF Aktiengesellschaft
- 当前专利权人地址: DEX Ludwigshafen
- 优先权: HUX1778/87 19870424
- 主分类号: A61K31/47
- IPC分类号: A61K31/47 ; A61P25/20 ; A61P25/22 ; C07D215/38
摘要:
The new compounds of the general Formula I ##STR1## (wherein R.sub.1 stands for C.sub.1-5 alkyl, C.sub.2-5 alkenyl, C.sub.2-5 alkinyl, C.sub.3-7 cycloalkyl or optionally substituted phenyl-(C.sub.1-4 alkyl);R.sub.2 represents hydrogen or C.sub.1-5 alkanoyl;X.sub.1 and X.sub.2 can be identical or different and each stands for hydrogen, halogen, trifluoromethyl or C.sub.1-4 alkoxy;(with the proviso that if R.sub.1 stands for ethyl, at least one of R.sub.2, X.sub.1 and X.sub.2 is different from hydrogen) and pharmaceutically acceptable acid additions salts possess valuable anxiolytic properties devoid of sedative effect and can be used in therapy.The compounds of the general Formula I can be prepared by methods known per se.
公开/授权文献
- US6092080A Digital library system 公开/授权日:2000-07-18
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