发明授权
- 专利标题: Tricyclic aromatic compounds
- 专利标题(中): 三环芳香族化合物
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申请号: US356884申请日: 1989-05-23
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公开(公告)号: US4923892A公开(公告)日: 1990-05-08
- 发明人: O. William Lever, Jr. , Harry J. Leighton
- 申请人: O. William Lever, Jr. , Harry J. Leighton
- 申请人地址: NC Research Triangle Park
- 专利权人: Burroughs Wellcome Co.
- 当前专利权人: Burroughs Wellcome Co.
- 当前专利权人地址: NC Research Triangle Park
- 优先权: GBX8520662 19850817
- 主分类号: C07C229/38
- IPC分类号: C07C229/38 ; C07D313/12 ; C07D313/14
摘要:
The present invention relates to compounds of formula I ##STR1## or a salt, ester or amide thereof; wherein R.sup.1 is --CH.sub.2 --CH.sub.2 --, CH.sub.2 --O-- or --O--CH.sub.2 --; R.sup.2 and R.sup.3 are the same or different and are each hydrogen, C.sub.1-4 alkyl or taken together with the nitrogen comprise a nitrogen-containing heterocyclic ring having four to six ring members; R.sup.4 is a single bond or a C.sub.1-7 bivalent aliphatic hydrocarbon group and may be joined to the aromatic ring system at the 2,3,8 or 9 positions; n is 0 to 3, and their use as antihistamine and antiasthma agents.
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