发明授权
- 专利标题: Process for the preparation of intermediates for the synthesis of diltiazem
- 专利标题(中): 制备用于合成地尔硫卓的中间体的方法
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申请号: US384730申请日: 1989-07-25
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公开(公告)号: US4937334A公开(公告)日: 1990-06-26
- 发明人: Silvia Cavicchioli , Maurizio Paiocchi , Claudio Giordano
- 申请人: Silvia Cavicchioli , Maurizio Paiocchi , Claudio Giordano
- 申请人地址: ITX Vicenza
- 专利权人: Zambon Group S.p.A.
- 当前专利权人: Zambon Group S.p.A.
- 当前专利权人地址: ITX Vicenza
- 优先权: ITX21479A/88 19880726
- 主分类号: A61K31/554
- IPC分类号: A61K31/554 ; C07D281/10
摘要:
A process for the preparation of the compound (2S,3S)(+)-3-hydroxy-2,3-dihydro-2-(4-methoxyphenyl)-5-(2-dimethylaminoethyl)-1, 5-benzothiazepin-4(5H)-one is described. Said compound is an intermediate useful in the synthesis of Diltiazem.