发明授权
- 专利标题: Polymers containing carboxy-ortho ester and ortho ester linkages
- 专利标题(中): 含羧基原酸酯和原酸酯键的聚合物
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申请号: US366125申请日: 1989-06-14
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公开(公告)号: US4946931A公开(公告)日: 1990-08-07
- 发明人: Jorge Heller , Steve Y. W. Ng , Donald W. H. Penhale
- 申请人: Jorge Heller , Steve Y. W. Ng , Donald W. H. Penhale
- 申请人地址: CA Menlo Park
- 专利权人: Pharmaceutical Delivery Systems, Inc.
- 当前专利权人: Pharmaceutical Delivery Systems, Inc.
- 当前专利权人地址: CA Menlo Park
- 主分类号: A61K9/20
- IPC分类号: A61K9/20 ; C08G63/00 ; C08G63/66
摘要:
Polymers are provided that are useful for making biodegradable sustained release agent dispensers and which contain at least one of the following mer units (I) and (II) ##STR1## wherein X is a quadrivalent organic grouping, A and B are hydrogen or lower alkyl, and R is hydrocarbyl or oxyhydrocarbyl of 1 to 14 carbon atoms and, if oxyhydrocarbyl, containing 1 to 4 oxy groups, and may be either aliphatic or aryl, unsubstituted or substituted with one or more lower alkyl, amino, nitro or halogen moieties. Methods of synthesizing the novel polymers are also provided, as biodegradable beneficial agent dispensers prepared using the novel polymers.
公开/授权文献
- US5578890A Crystal resonator package 公开/授权日:1996-11-26
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