发明授权
- 专利标题： Collagen wound healing matrices and process for their production
- 专利标题（中）： 胶原伤口愈合基质及其生产工艺
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申请号： US286303申请日： 1988-12-16
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公开(公告)号： US4950483A公开(公告)日： 1990-08-21
- 发明人: George Ksander , Yasushi Ogawa
- 申请人： George Ksander , Yasushi Ogawa
- 申请人地址： CA Palo Alto
- 专利权人： Collagen Corporation
- 当前专利权人： Collagen Corporation
- 当前专利权人地址： CA Palo Alto
- 主分类号： A61K38/00
- IPC分类号： A61K38/00 ; A61F2/00 ; A61K38/17 ; A61K38/21 ; A61K38/22 ; A61K38/27 ; A61K38/39 ; A61L27/00 ; A61L27/24 ; A61L27/54 ; A61P7/00 ; A61P17/00 ; A61P35/00 ; A61P37/00 ; A61P43/00
摘要：
Collagen implants that are useful as wound healing matrices are characterized by being formed of collagen fibrils that are not chemically cross-linked, and having a bulk density of 0.01 to 0.3 g/cm.sup.3 and a pore population in which at least about 80% of the pores have an average pore size of 35 to 250 microns. The implants are capable of promoting connective tissue deposition, angiogenesis, reepithelialization, and fibroplasia. The wound healing matrix also serves an an effective sustained delivery system for synergistic combinations of FGF and TGF-B.
公开/授权文献
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