发明授权
US4959303A Assay for antigens by binding immune complexes to solid supports free of
protein and non-ionic binders
失效
通过将免疫复合物与不含蛋白质和非离子粘合剂的固体支持物结合来测定抗原
- 专利标题： Assay for antigens by binding immune complexes to solid supports free of protein and non-ionic binders
- 专利标题（中）： 通过将免疫复合物与不含蛋白质和非离子粘合剂的固体支持物结合来测定抗原
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申请号： US135869申请日： 1987-12-21
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公开(公告)号： US4959303A公开(公告)日： 1990-09-25
- 发明人: Gary L. Milburn , Judith Rabbie , Thomas M. Houts
- 申请人： Gary L. Milburn , Judith Rabbie , Thomas M. Houts
- 申请人地址： CA Palo Alto
- 专利权人： Syntex (U.S.A.) Inc.
- 当前专利权人： Syntex (U.S.A.) Inc.
- 当前专利权人地址： CA Palo Alto
- 主分类号： G01N33/543
- IPC分类号： G01N33/543 ; G01N33/569 ; G01N33/571
摘要：
Methods are disclosed for detecting an antigen in a biological sample. The methods involve providing in combination a solid support, which is substantially free of specific binding proteins, and a medium comprising an antigen from the sample and an antibody for the antigen. The combination is incubated under conditions sufficient for the antibody when bound to the antigen to bind to the support. The presence or amount of antibody on the support or in the medium is determined and is related to the presence of antigen in the sample. The methods have particular application to the detection of gram-negative bacteria.
公开/授权文献
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