发明授权
US4978622A Cytophaga-derived immunopotentiator 失效
细胞因子来源的免疫增强剂

Cytophaga-derived immunopotentiator
摘要:
Substantially pigment-free gliding bacteria adjuvant (GBA) is isolated from medium in which Cytophaga strain GB-2 has been cultured by extraction with acetone to remove pigment, enzymatic digestion and filtration to remove residual protein and nucleic acids, and affinity chromatography to remove residual lipopolysaccharide. This pure form of GBA shows unexpectedly high specific immunopotentiating activity relative to crude GBA.
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