Invention Grant
US4983513A Sulfhydryl compounds for suppressing the inhibitory effects of NAD
degradation products on LD-L activity
失效
用于抑制NAD降解产物对LD-L活性的抑制作用的巯基化合物
- Patent Title: Sulfhydryl compounds for suppressing the inhibitory effects of NAD degradation products on LD-L activity
- Patent Title (中): 用于抑制NAD降解产物对LD-L活性的抑制作用的巯基化合物
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Application No.: US845883Application Date: 1986-03-28
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Publication No.: US4983513APublication Date: 1991-01-08
- Inventor: Tsung-I Lin , Alice C. Liu
- Applicant: Tsung-I Lin , Alice C. Liu
- Applicant Address: CA Fullerton
- Assignee: Beckman Instruments, Inc.
- Current Assignee: Beckman Instruments, Inc.
- Current Assignee Address: CA Fullerton
- Main IPC: C07H19/207
- IPC: C07H19/207 ; C07H21/02 ; C12Q1/00
Abstract:
A liquid coenzyme reagent comprises the coenzyme nicotinamide adenine dinucleotide (NAD), or nicotinamide adenine dinucleotide phosphate (NADP), and a sulfhydryl compound capable of counteracting the inhibitory effects of NAD (or NADP) degradation products on LD-L activity. The reagent is maintained at a pH of less than about 31/2. The liquid reagent has a shelf life of at least about 2 years, maintaining a LD-L activity of at least 90% that of the reagent when fresh, when stored at a temperature of from 2.degree.-8.degree. C.
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