Sulfhydryl compounds for suppressing the inhibitory effects of NAD
degradation products on LD-L activity
    1.
    发明授权
    Sulfhydryl compounds for suppressing the inhibitory effects of NAD degradation products on LD-L activity 失效
    用于抑制NAD降解产物对LD-L活性的抑制作用的巯基化合物

    公开(公告)号:US4983513A

    公开(公告)日:1991-01-08

    申请号:US845883

    申请日:1986-03-28

    CPC classification number: C12Q1/008 C07H19/207 C07H21/02

    Abstract: A liquid coenzyme reagent comprises the coenzyme nicotinamide adenine dinucleotide (NAD), or nicotinamide adenine dinucleotide phosphate (NADP), and a sulfhydryl compound capable of counteracting the inhibitory effects of NAD (or NADP) degradation products on LD-L activity. The reagent is maintained at a pH of less than about 31/2. The liquid reagent has a shelf life of at least about 2 years, maintaining a LD-L activity of at least 90% that of the reagent when fresh, when stored at a temperature of from 2.degree.-8.degree. C.

    Abstract translation: 液体辅酶试剂包括辅酶烟酰胺腺嘌呤二核苷酸(NAD)或烟酰胺腺嘌呤二核苷酸磷酸(NADP),以及能够抵消NAD(或NADP)降解产物对LD-L活性的抑制作用的巯基化合物。 试剂保持在小于约31/2的pH。 液体试剂的保存期至少约2年,当保存在2℃-8℃的温度下时,维持新鲜时的试剂的LD-L活性至少为90%。

Patent Agency Ranking