发明授权
US4985458A Catechol diacetate derivatives for inducing the production of nerve
growth factor to treat degenerative diseases in the central nervous
system
失效
儿茶酚二乙酸酯衍生物用于诱导神经生长因子的产生以治疗中枢神经系统中的退行性疾病
- 专利标题： Catechol diacetate derivatives for inducing the production of nerve growth factor to treat degenerative diseases in the central nervous system
- 专利标题（中）： 儿茶酚二乙酸酯衍生物用于诱导神经生长因子的产生以治疗中枢神经系统中的退行性疾病
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申请号： US481677申请日： 1990-02-20
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公开(公告)号： US4985458A公开(公告)日： 1991-01-15
- 发明人: Shigenobu Nakayama , Fumiaki Ikeda
- 申请人： Shigenobu Nakayama , Fumiaki Ikeda
- 申请人地址： JPX Tokyo
- 专利权人： Mitsui Toatsu Chemicals, Incorporated
- 当前专利权人： Mitsui Toatsu Chemicals, Incorporated
- 当前专利权人地址： JPX Tokyo
- 优先权： JPX61-226135 19860926; JPX61-303761 19861222; JPX62-035697 19870220; JPX62-128444 19870527
- 主分类号： A61K31/05
- IPC分类号： A61K31/05 ; A61K31/22 ; A61K31/335 ; A61K31/36 ; C07D317/46 ; C07D319/20
摘要：
A pharmaceutical composition for the treatment of regressive disorders of the central nervous system treatable by inducing the production and secretion of nerve growth factor, containing as an active ingredient a catechol derivative of the formula ##STR1## where R.sub.6 is a lower alkyl group having 2 to 5 carbon atoms. The catechol derivatives provide preventative and remedial effects for regressive disorders in the central nervous system including senile dementia of the alzheimer type.
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