Invention Grant
US4996201A 4-(N-substituted amino)-2-butynyl-1-carbamates and thiocarbamates and
derivatives thereof as centrally acting muscarinic agents
失效
4-（N-取代氨基）-2-丁炔基-1-氨基甲酸酯和硫代氨基甲酸酯及其衍生物作为中枢作用毒蕈碱药
- Patent Title: 4-(N-substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof as centrally acting muscarinic agents
- Patent Title (中): 4-（N-取代氨基）-2-丁炔基-1-氨基甲酸酯和硫代氨基甲酸酯及其衍生物作为中枢作用毒蕈碱药
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Application No.: US388777Application Date: 1989-08-02
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Publication No.: US4996201APublication Date: 1991-02-26
- Inventor: Stephen C. Bergmeier , Jeffrey A. Kester , Walter H. Moos , Haile Tecle , Anthony J. Thomas
- Applicant: Stephen C. Bergmeier , Jeffrey A. Kester , Walter H. Moos , Haile Tecle , Anthony J. Thomas
- Applicant Address: NJ Morris Plains
- Assignee: Warner-Lambert Co.
- Current Assignee: Warner-Lambert Co.
- Current Assignee Address: NJ Morris Plains
- Main IPC: A61K31/27
- IPC: A61K31/27 ; A61K31/40 ; A61K31/495 ; A61K31/535 ; A61K31/5375 ; A61P25/02 ; A61P25/28 ; C07C271/20 ; C07C271/24 ; C07C271/28 ; C07C333/04 ; C07D205/04 ; C07D211/14 ; C07D211/22 ; C07D295/12 ; C07D295/125
Abstract:
4-(N-Substituted amino)-2-butynyl-1-carbamates and thiocarbamates and derivatives thereof are described, as well as methods for the preparation and pharmaceutical compositions of same, which are useful as centrally acting muscarinic agents and are useful as analgesic agents for the treatment of pain, as sleep aids and as agents for treating the symptoms of senile dementia, Alzheimer's disease, Huntington's chorea, tardive dyskinesia, hyperkinesia, mania, or similar conditions of cerebral insufficiency characterized by decreased cerebral acetylcholine production or release.
Public/Granted literature
- US6104342A Scanned antenna array comprising a ferrite scanning line source Public/Granted day:2000-08-15
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