发明授权
- 专利标题: Indole derivatives
- 专利标题(中): 吲哚衍生物
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申请号: US477466申请日: 1990-02-09
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公开(公告)号: US5001135A公开(公告)日: 1991-03-19
- 发明人: Alexander W. Oxford , Peter C. North , Martin R. Johnson
- 申请人: Alexander W. Oxford , Peter C. North , Martin R. Johnson
- 申请人地址: GB2 London
- 专利权人: Glaxo Group Limited
- 当前专利权人: Glaxo Group Limited
- 当前专利权人地址: GB2 London
- 优先权: GBX8903036 19890210
- 主分类号: C07D211/26
- IPC分类号: C07D211/26 ; A61K31/00 ; A61K31/4427 ; A61K31/445 ; A61K31/4465 ; A61K31/4523 ; A61K31/454 ; A61P9/00 ; A61P25/04 ; A61P25/06 ; A61P43/00 ; C07D401/04
摘要:
Compounds are disclosed of formula (I) ##STR1## wherein R.sub.1 represents a C.sub.1-6 alkyl group;R.sub.2 represents a hydrogen atom or a C.sub.1-3 alkyl group;n represents zero or an integer from 1 to 3;and pharmaceutically acceptable salts thereof.The compounds are useful for the treatment of migraine, cluster headache, chronic paroxysmal hemicrania and headache associated with vascular disorders.Processes and intermediates for their preparation and pharmaceutical compositions containing them are also disclosed.
公开/授权文献
- US5855311A Reloadable surgical instrument 公开/授权日:1999-01-05
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