发明授权
US5015642A Benzothiazinone oxides, processes for their preparation, medicaments
containing them and the use thereof, and intermediates for their
preparation
失效
苯并噻嗪酮氧化物，其制备方法，含有它们的药物及其用途，以及其制备中间体
- 专利标题： Benzothiazinone oxides, processes for their preparation, medicaments containing them and the use thereof, and intermediates for their preparation
- 专利标题（中）： 苯并噻嗪酮氧化物，其制备方法，含有它们的药物及其用途，以及其制备中间体
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申请号： US230407申请日： 1988-08-10
-
公开(公告)号： US5015642A公开(公告)日： 1991-05-14
- 发明人: Ulrich Lerch , Rainer Henning , Hansjorg Urbach , Joachim Kaiser
- 申请人： Ulrich Lerch , Rainer Henning , Hansjorg Urbach , Joachim Kaiser
- 申请人地址： DEX Frankfurt am Main
- 专利权人： Hoechst Aktiengesellschaft
- 当前专利权人： Hoechst Aktiengesellschaft
- 当前专利权人地址： DEX Frankfurt am Main
- 优先权： DEX3726759 19870812
- 主分类号： A61K31/54
- IPC分类号： A61K31/54 ; A61K31/5415 ; A61P3/00 ; A61P3/14 ; A61P9/00 ; C07D279/16 ; C07D417/12
摘要：
Compounds I ##STR1## in which R(1) and R(4) equal H, alkyl, alkoxy, Hal, CF.sub.3, NO.sub.2, OH, acetamido or amino;R(2) equals H, alk(en)yl or phenylalkyl (optionally substituted);R(3) equals H, (cyclo)alk(en)yl-(alkyl), phenyl or phenylalkyl (optionally substituted);A equal CHOH, CO, CH.dbd.CH, C.tbd.C, CH.sub.2, O or S;m equals 1 or 2;n equals 1 to 3;p equals 0 to 4;R(5) equals some amino groups, and their salts, exhibit excellent calcium-antagonistic activity.Processes for their preparation are described.
公开/授权文献
- US5643591A Solid dosage forms 公开/授权日：1997-07-01
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