Invention Grant
- Patent Title: Electrically-charged nerve guidance channels
- Patent Title (中): 电荷神经引导通道
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Application No.: US621081Application Date: 1990-11-30
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Publication No.: US5030225APublication Date: 1991-07-09
- Inventor: Patrick Aebischer , Robert F. Valentini
- Applicant: Patrick Aebischer , Robert F. Valentini
- Applicant Address: RI Providence
- Assignee: Brown University Research Foundation
- Current Assignee: Brown University Research Foundation
- Current Assignee Address: RI Providence
- Main IPC: A61B17/00
- IPC: A61B17/00 ; A61B17/11 ; A61F2/00 ; A61L31/04 ; A61L31/14
Abstract:
A medical device is disclosed for use in regenerating a severed nerve. The device includes an implantable, tubular, electrically-charged membrane having openings adapted to receive the ends of the severed nerve and a lumen having a diameter ranging from about 0.5 millimeters to about 2.0 centimeters to permit regeneration of the nerve therethrough. The membrane is fabricated such that an electric charge is exhibited at the inner membrane surface to stimulate regeneration by axonal sprouting and process extension. Also disclosed are methods for repairing a severed nerve and for preparing a medical device for use in regeneration of a severed nerve.
Public/Granted literature
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