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US5041607A Process for crystallizing L-alpha-aspartyl-L-phenyl-alanine methyl 失效
用于结晶L-α-天冬氨酰-L-苯基 - 丙氨酸甲基的方法

Process for crystallizing L-alpha-aspartyl-L-phenyl-alanine methyl
摘要:
A crystalline L-alpha-aspartyl-L-phenyl-alanine methyl ester product is disclosed. The product is obtained by crystallizing the ester from an aqueous solution, by cooling. The initial concentration of ester in the aqueous solution used provides at least 10 grams of precipitated solid phase per liter of solution. The solution is cooled through conductive heat transfer without effecting forced flow to form a sherbet-like pseudo solid phase.
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