发明授权
- 专利标题: Stabilization of enteric coated dosage form
- 专利标题(中): 肠溶包衣剂形式的稳定化
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申请号: US379727申请日: 1989-07-14
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公开(公告)号: US5068110A公开(公告)日: 1991-11-26
- 发明人: Mahdi B. Fawzi , Daniel A. Kubert , Kuchi S. Murthy
- 申请人: Mahdi B. Fawzi , Daniel A. Kubert , Kuchi S. Murthy
- 申请人地址: NJ Morris Plains
- 专利权人: Warner-Lambert Company
- 当前专利权人: Warner-Lambert Company
- 当前专利权人地址: NJ Morris Plains
- 主分类号: A61K9/48
- IPC分类号: A61K9/48
摘要:
The present invention is a stabilized enteric-coated pharmaceutical dosage form and processes for the preparation thereof. Dissolution stability after storage of the dosage form under high stress conditions is improved by an enteric-coated dosage form having an enteric coating wherein the coating is of the acrylic resin kind of from 14 mg/cm.sup.2 to 24 mg/cm.sup.2 or an enteric coating wherein the coating is of the acetate kind of from 14 mg/cm.sup.2 to 24 mg/cm.sup.2 and having a second coating of hydrophilic coating for example, hydroxypropyl cellulose, hydroxymethyl cellulose or hydroxypropylmethyl cellulose.
公开/授权文献
- US5636579A Security window adapted to prevent forced entry 公开/授权日:1997-06-10
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