发明授权
US5086053A Derivatives of 1,3,4-thiadiazole, a method of obtaining them and
pharmaceutical compositions containing them
失效
1,3,4-噻二唑的衍生物,获得它们的方法和含有它们的药物组合物
- 专利标题: Derivatives of 1,3,4-thiadiazole, a method of obtaining them and pharmaceutical compositions containing them
- 专利标题(中): 1,3,4-噻二唑的衍生物,获得它们的方法和含有它们的药物组合物
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申请号: US394321申请日: 1989-08-16
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公开(公告)号: US5086053A公开(公告)日: 1992-02-04
- 发明人: Roger Brodin , Dominique Olliero , Paul Worms
- 申请人: Roger Brodin , Dominique Olliero , Paul Worms
- 申请人地址: FRX Paris
- 专利权人: Sanofi
- 当前专利权人: Sanofi
- 当前专利权人地址: FRX Paris
- 优先权: FRX8811226 19880825
- 主分类号: C07D285/12
- IPC分类号: C07D285/12 ; A61K31/41 ; A61K31/433 ; A61K31/44 ; A61K31/445 ; A61K31/495 ; A61K31/535 ; A61P25/00 ; C07D285/135 ; C07D417/04 ; C07D417/12
摘要:
The present invention relates to thiadiazole derivatives having the formula: ##STR1## in which: R.sub.1 represents a phenyl group, non-substituted or substitued 1 to 3 times by a halogen atom, preferably chlorine or fluorine, or by a C.sub.1 -C.sub.4 alkyl group, preferably the methyl group, or by a C.sub.1 -C.sub.4 alkoxy group, preferably the methoxy group, or by a hydroxy group or by a trifluoromethyl group or a phenyl group substituted simultaneously by 1 to 3 halogen atoms and by 1 or 2 methyl groupings;R.sub.2 represents hydrogen or a C.sub.1 -C.sub.4 alkyl group,R.sub.3 represents an alkylamino group or a heterocyclic group,Application: Drugs for treatment of notably senile dementia.
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