发明授权
US5118617A SAF polypeptide, gene coding therefor, SAF promoter and expression
methods for expressing foreign DNA sequences in streptomyces
失效
SAF多肽，其基因编码，SAF启动子和表达方法，用于表达STRETOMYCES中的外源DNA序列
- 专利标题： SAF polypeptide, gene coding therefor, SAF promoter and expression methods for expressing foreign DNA sequences in streptomyces
- 专利标题（中）： SAF多肽，其基因编码，SAF启动子和表达方法，用于表达STRETOMYCES中的外源DNA序列
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申请号： US410706申请日： 1989-09-22
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公开(公告)号： US5118617A公开(公告)日： 1992-06-02
- 发明人: Antonio D. Ortega , Jose A. Gil , Tomas V. Garcia , Juan F. Martin
- 申请人： Antonio D. Ortega , Jose A. Gil , Tomas V. Garcia , Juan F. Martin
- 申请人地址： ANX Curacao
- 专利权人： Applied Research Systems ARS Holding N.V.
- 当前专利权人： Applied Research Systems ARS Holding N.V.
- 当前专利权人地址： ANX Curacao
- 主分类号： C12N15/09
- IPC分类号： C12N15/09 ; C07K14/00 ; C07K14/36 ; C07K14/37 ; C07K14/41 ; C12N20060101 ; C12N1/21 ; C12N15/11 ; C12N15/31 ; C12N15/63 ; C12N15/67 ; C12P1/00 ; C12P21/02 ; C12R1/465
摘要：
The cloning and characterization of a newly isolated gene, referred to as saf (secondary metabolism activation factor) is disclosed. This gene encodes a new amino acid polypeptide, referred to as the SAF polypeptide, which directly or indirectly modulates the expression of extracellular enzymes in Streptomyces. DNA units or fragments which encode the SAF polypeptides are also disclosed, as are vectors containing said DNA, host organisms transformed with such vectors, and processes for preparing extracellular enzymes or heterologous polypeptides by culturing such host organisms.
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