发明授权
- 专利标题： Cocaine receptor binding ligands
- 专利标题（中）： COCAINE RECEPTOR BINDING LIGANDS
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申请号： US564755申请日： 1990-08-09
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公开(公告)号： US5128118A公开(公告)日： 1992-07-07
- 发明人: Frank I. Carroll , Anita H. Lewin , Philip Abraham , Michael J. Kuhar , John W. Boja
- 申请人： Frank I. Carroll , Anita H. Lewin , Philip Abraham , Michael J. Kuhar , John W. Boja
- 申请人地址： NC Research Triangle Park
- 专利权人： Research Triangle Institute
- 当前专利权人： Research Triangle Institute
- 当前专利权人地址： NC Research Triangle Park
- 主分类号： A61K51/00
- IPC分类号： A61K51/00 ; C07D451/02 ; C07F7/22 ; G01N33/50
摘要：
3.beta.-[4-iodophenyl]-tropan-2.beta.-carboxylic acid methyl ester tartrate is a high affinity binding ligand for neurotransmitters in mammalian brains. It and its congeners may be employed for imaging and other brain scanning techniques that allow the determination of the presence of cocaine receptors, such as neurotransmitters and the like.
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