发明授权
US5141813A Multifunctional controlled pore glass reagent for solid phase
oligonucleotide synthesis
失效
用于固相寡核苷酸合成的多功能可控孔隙玻璃试剂
- 专利标题： Multifunctional controlled pore glass reagent for solid phase oligonucleotide synthesis
- 专利标题（中）： 用于固相寡核苷酸合成的多功能可控孔隙玻璃试剂
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申请号： US399658申请日： 1989-08-28
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公开(公告)号： US5141813A公开(公告)日： 1992-08-25
- 发明人: Paul S. Nelson
- 申请人： Paul S. Nelson
- 申请人地址： CA Palo Alto
- 专利权人： Clontech Laboratories, Inc.
- 当前专利权人： Clontech Laboratories, Inc.
- 当前专利权人地址： CA Palo Alto
- 主分类号： C07H21/00
- IPC分类号： C07H21/00
摘要：
The subject invention concerns a novel multifunctional solid support reagent which is useful in solid phase oligonucleotide synthesis. Specifically, the reagent is used in a solid phase oligonucleotide process to chemically modify the 3' terminus of a synthetic oligonucleotide with any chemical functional group. The invention reagent can be used to construct 3' labeled oligonucleotide hybridization probes to detect the presence of a target polynucleotide in biological and clinical samples.
公开/授权文献
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