发明授权
- 专利标题: Tricyclic thromboxane A.sub.2 antagonists
- 专利标题(中): 三环血栓素A2拮抗剂
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申请号: US616095申请日: 1990-11-20
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公开(公告)号: US5143922A公开(公告)日: 1992-09-01
- 发明人: Etsuo Oshima , Hiroyuki Obase , Akira Karasawa , Kazuhiro Kubo , Ichiro Miki , Akio Ishii , Hidee Ishii , Kenji Ohmori
- 申请人: Etsuo Oshima , Hiroyuki Obase , Akira Karasawa , Kazuhiro Kubo , Ichiro Miki , Akio Ishii , Hidee Ishii , Kenji Ohmori
- 申请人地址: JPX Tokyo
- 专利权人: Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人: Kyowa Hakko Kogyo Co., Ltd.
- 当前专利权人地址: JPX Tokyo
- 优先权: JPX62-315769 19871214; JPX63-23543 19880203
- 主分类号: C07D211/14
- IPC分类号: C07D211/14 ; C07D313/12 ; C07D333/34 ; C07D405/06 ; C07D405/12 ; C07D405/14 ; C07D407/12 ; C07D409/12 ; C07D471/10
摘要:
Novel tricyclic compounds having a TXA.sub.2 antagonizing activity represented by formula (I): ##STR1## possess a potent antagonizing action against thromboxane A.sub.2 and also an antiallergic and/or antihistaminic acitvity, and are expected to have preventive and therapeutic effects on ischemic diseases, cerebro-vascular diseases, etc.
公开/授权文献
- US5729823A Cemented carbide with binder phase enriched surface zone 公开/授权日:1998-03-17
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