The invention provides a novel method of manufacturing a semiconductor device comprising those sequential steps including the following, formation of a floating gate electrode on a region predetermined for the formation of the first conductive channel across an insulation film, followed by superimposition of a control gate electrode on the floating gate electrode across another insulation film. After completing the formation of the stacked gate electrode unit, the first conductive impurities are injected into silicon substrate by applying a minimum of 8 degrees of angle against the normal of this substrate under aid of ionic injection, and then forms a region containing strong density of the first conductive impurities adjacent to the boundary of a layer of diffused second conductive impurities which is at least predetermined to become the drain region of the transistor incorporating the stacked gate electrode unit. As a result of the provision of the region containing strong density of impurities injected in the oblique direction, the efficiency in the writing of data into the floating gate electrode is significantly promoted, and at the same time occurrence of "short-channel" effect can securely be suppressed as well.