发明授权
US5196427A 3-aryl-4(3H) quinazolinone CCK antagonists and pharmaceutical
formulations thereof
失效
（3H）喹唑啉酮CCK拮抗剂及其药物制剂
- 专利标题： 3-aryl-4(3H) quinazolinone CCK antagonists and pharmaceutical formulations thereof
- 专利标题（中）： （3H）喹唑啉酮CCK拮抗剂及其药物制剂
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申请号： US763104申请日： 1991-09-20
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公开(公告)号： US5196427A公开(公告)日： 1993-03-23
- 发明人: Melvin J. Yu , Jefferson R. McCowan , K. Jeff Thrasher
- 申请人： Melvin J. Yu , Jefferson R. McCowan , K. Jeff Thrasher
- 申请人地址： IN Indianapolis
- 专利权人： Eli Lilly and Company
- 当前专利权人： Eli Lilly and Company
- 当前专利权人地址： IN Indianapolis
- 主分类号： C07D403/06
- IPC分类号： C07D403/06
摘要：
Novel substituted quinazolinones have been found to exhibit specific binding to cholecystokinin (CCK) receptors in the brain and/or peripheral site such as the pancreas and ileum. The quinazolinones are CCK receptor antagonists and find therapeutic application in the treatment of gastrointestinal disorders and central nervous system disorders, and are useful for appetite regulation in mammals. Pharmaceutical formulations for such indications are described.
公开/授权文献
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